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The conditions that have been associated with glutathione deficiency include the following: Neurodegenerative diseases such as Alzheimers, Parkinsons and Huntingtons disease and ALS Pulmonary diseases such as COPD, asthma, and acute respiratory distress syndrome Immune system disorders Cardiovascular diseases such as high blood pressure, elevated cholesterol, and heart attacks Chronic age-related disorders such as cataracts, macular degeneration, hearing impairment, and glaucoma Liver disease Cystic fibrosis Aging processes (Pizzorno, 2014)

Sequencing adapters were trimmed following quality checks on the reads performed using FastQC 86 (v0.11.9)

205 ACSL1 promotes peritoneal metastasis of ovarian cancer cells by reducing lipid peroxidation by lipid reprogramming

l-glutamine (Fisher Scientific, 25030081), l-methionine (Sigma-Aldrich, M5308), l-cystine (Sigma-Aldrich, C7602), GSH (Sigma-Aldrich, G4251) or cysteinylglycine (Bachem, 4002969) was added to each condition at the indicated concentrations

However, the role of isoforms of NOS in this process remains to be elucidated (231, 232)

Antibiotic-induced cardiac arrhythmias