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Today we are aware that the primary culprit for rheumatoid arthritis is citrullination, the modification of arginine into citrulline, the amino acid which triggers the immune response

Appl Microbiol Biotechnol 36:538840 Awano N, Wada M, Kohdoh A, Oikawa T, Takagi H, Nakamori S (2003) Effect of cysteine desulfhydrase gene disruption on l-cysteine overproduction in Escherichia coli

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