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It consists largely of three amino acids: glutamine, glycine, and cysteine

While both pathways maintain cellular homeostasis by clearing defective mitochondria, mitoptosis achieves this through self-encapsulation and extracellular expulsion, whereas mitophagy relies on lysosomal degradation

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Moriarty-Craige SE, Jones DP

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Collectively, these data confirm the functional absence of MZB in Gclc fl/fl Mb1-Cre + mice and demonstrate that Gclc is critical for FoB-mediated GC reactions and antibody-mediated immunity to infections