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If there is a lack of cobalamin in the body, methylmalonyl CoA accumulates, which presumably leads to the neurological manifestations of B12 deficiency.[4][7][9][12] The replenishment with parenteral cyanocobalamin causes a rapid and complete improvement of megaloblastic anemia and gastrointestinal symptoms caused by vitamin B12 deficiency

Dormancy Period: The incubation period in humans is usually from 1 week to 47 days after infection

doi: 10.1038/s43587-021-00121-8 [DOI] [PMC free article] [PubMed] [Google Scholar] 141.Lus C, Maduro AT, Pereira P, Mendes JJ, Soares R, Ramalho R

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The DNA compositions will generally include a coding region which encodes a polypeptide comprising an amino acid sequence substantially homologous to the amino acid sequence of a PfEMPl protein

coli using the sulfoxide synthase from Methylobacterium strains