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We defined a set of controls as individuals with none of the ten known pathogenic mtDNA variants tested

The NFKB family of transcription factors activate several groups of genomic sequences, including proviral DNA sequences that have been incorporated in the infected host cells (e.g., HIV proviral DNA has been successfully studied in a number of peer-reviewed publications

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Donowitz JR, Alam M, Kabir M, et al

doi:10.1371/journal.pone.0100481 474. Podgaec S, Rizzo LV, Fernandes LF, Baracat EC, Abrao MS