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doi: 10.1182/blood-2017-06-740944 3 YongJCaiSZengZ

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That deep, painful cyst isn't just a clogged pore

Beyond plasmin generation, uPAR influences cell adhesion and signaling by interacting with various cell surface proteins, including integrins (51, 31, v3, v5), vitronectin, GPCRs, RTKs (e.g., EGF receptor and PDGF receptor), and the very low-density lipoprotein receptor [194197]