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3 (2016): 97-98 McCarthy, Grace C., Sohair A

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While this creates therapeutic vulnerabilities, conventional metabolic inhibitors face critical limitations in systemic toxicity, metabolic heterogeneity, and inadequate tumor accumulation

For the metabolomics of cell cultures, cells were differentiated in 6-well plates

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Although direct interaction between 4-HNE and caspase-3 in psoriatic tissue is not fully confirmed, elevated caspase-3 activity and increased 4-HNE-protein adduct formation support its pro-apoptotic role [47,48]