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Catabolism of monosaccharides in cancer cytoplasm Once inside the cytoplasm, glucose commits to catabolism through phosphorylation to glucose-6-phosphate (Fig

& Skinner, M

A., Rijo-Ferreira, F., Green, C

Moreover, AMPK also stimulates autophagy independently of the mTOR signaling pathway through activating phosphorylation of ULK1 (Kim et al., 2011) (Figure 5)