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In addition to a potentially direct antioxidant activity, curcumin can induce the expression of phase II antioxidant enzymes, including glutamate-cysteine ligase (GCL), the rate-limiting enzyme in glutathione synthesis

Collectively, these findings underscore the critical role of the interplay between Nrf2 and autophagy in the pathogenesis of RA

doi: 10.1016/j.neuint.2016.10.001

Zhao, Z., Dong, R., Cui, K., You, Q

This method includes needling 1525 toward the vertebrae, and after producing a needling sensation (getting the qi) along the distribution of nerves, the tread can be embedded (the lesion must not be painful when touched) [30]