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The Increlex label cites preclinical 2-year rat carcinogenicity studies in which increased mammary and skin tumor incidence occurred at high IGF-1 exposure

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Blood glucose monitoring is standard in rodent studies using IGF-1 LR3, particularly at doses above 1 mg/kg

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Drug-disease interaction and time-dependent population pharmacokinetics of isatuximab in relapsed/refractory multiple myeloma patients