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Reversible inactivation of alpha-ketoglutarate dehydrogenase in response to alterations in the mitochondrial glutathione status

Nevertheless, if we compare the internal states corresponding to Nrf2Keap1 complexes (Fig 3D), the dissociation model predicts an immediate decrease in the complex upon exposure to DEM followed by a sharp increase in complex formation, while the hinge-latch model predicts a prolonged increase in the complex that starts immediately upon oxidative stress

Glycolysis does not require oxygen, and the final product of this pathway is lactate

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Oral tranexamic acid had an edge over oral glutathione in our study