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doi: 10.1007/s11357-023-00935-x [DOI] [PMC free article] [PubMed] [Google Scholar] 149.Guan G, Chen Y, Dong Y

a pretreatment with methadone but not with morphine produced a cross-desensitization with [D-Ala 2 , D-Leu 5 ]-enkephalin (DADLE) and morphine (Liu et al., 1999a)

& Van Hoesen, G

Comparative effects of long-acting beta2-agonists, leukotriene receptor antagonists, and a 5-lipoxygenase inhibitor on exercise-induced asthma [In Process Citation]

doi: 10.1136/gutjnl-2020-323020 192 YueY.MaW.AccorsiE

Furthermore, methadone is also an N -methyl-d-aspartate (NMDA) receptor antagonist, and this property has been implicated in a role of preventing tolerance to methadone