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Description

Playing the DISC: turning on TRAIL death receptor-mediated apoptosis in cancer

For toxicity testing performed over a 12-day experimental period, tissues were daily exposed to 3 different concentrations of each test material for 30 min or 6 h (for detailed information on each material see Table 1)

It also shows how environmental factors like infections and toxins amplify this dysregulation, and how functional testing can illuminate root contributors and guide targeted interventions