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Use as directed by your veterinarian

[11] Long-term metformin therapy reduces calcium-dependent intrinsic-factor binding, lowering B12 absorption and potentially necessitating higher or more frequent parenteral doses

See also [edit] References [edit] "Inorganic Cyanide as Protecting Group in the Stereospecific Reconstitution of Vitamin B 12 from an Artificial Green Secocorrinoid" (PDF)