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Description

10.1002/j.1460-2075.1995.tb00205.x EMBO J

10.1016/S0140-6736(15)01341-0 62 LewisC.HillM.ChittyL

Additionally, E2 is known to be able to signal through the insulin-like growth factor 1 receptor (IGF-1R) in the skin in a non-genomic manner and this process has been implicated in the regulation of cutaneous aging (Serizawa et al., 2017)