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Non-mitochondrial oxygen consumption rate (OCR) was determined by injection with Antimycin A and rotenone, and residual oxygen consumption was subtracted from the results to obtain mitochondrial-specific rates

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In vitro studies have confirmed that molecular oxygen, superoxide, and H 2 O 2 all have the capacity to oxidize thiols, and among these H 2 O 2 stands out (Winterbourn and Metodiewa, 1999