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10.2147/OPTH.S35139 Clin

REF-0232 (v7.0) 1/2021

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In contrast, iron deficiency leads to adaptive responses that involve an increase in the activity of iron-transporters in the small intestine as well as morphological adaptations in the intestinal mucosa such as an increase in its thickness and the length of the villi to enhance the absorption of iron by enterocytes [102]

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Increased salt intake leads to higher sodium concentrations, leading to stiffening of endothelial cells and reduced release of nitric oxide from vascular endothelial cells ( 4.2 Mediterranean diet The Mediterranean diet, a traditional dietary pattern originating in the countries bordering the Mediterranean Sea, is widely regarded as one of the healthiest diets in the world due to its abundance of vegetables, fruits, whole grains, legumes, nuts, olive oil, and moderate amounts of fish and wine ( 5 Nutrients and glaucoma Nutrient intake is recognized as a potential factor influencing glaucoma onset and progression (Figure 1)