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A combination of folate and cobalamin has also been successfully used in rodents, in which it reduced cardiac damage in a model of isoproterenol-induced myocardial infarction in rats with HHCY [231], proving the ability of such supplementation to lower homocysteine levels with subsequent protection of the heart

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Interestingly, vitamin B12 deficiency itself can sometimes affect neurological function, potentially including the nerves that control bowel function, so treating a deficiency may actually improve rather than cause bowel symptoms in some cases

Improved Sleep: NAD+ treatment has been shown to positively impact sleep patterns, potentially leading to improved sleep quality and circadian rhythm regulation

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