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2016 Jan 15;310(2):H15373

But beneath the surface of glossy marketing and fitness fantasies lies a far more sobering truth: many of these substances operate in a medical grey zone, with unknown long-term risks, questionable manufacturing standards, and in some cases, life-threatening side-effects

Additionally, nanocopper undergoes rapid dissolution, releasing Cu + and Cu 2+ ions that interact with membrane phospholipids and intracellular targets, thereby amplifying oxidative stress (Wei et al., 2024)