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Even though the pathogenesis of autoimmune diseases is not yet fully elucidated, qualitative or quantitative alterations of T cells are undoubtedly central to the regulation of autoimmune diseases

Zhang D, Wang H, Liu H, Tao T, Wang N, Shen A

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Rich P, Gooderham M, Bachelez H, Goncalves J, Day RM, Chen R, Crowley J (2016) Apremilast, an oral phosphodiesterase 4 inhibitor, in patients with difficult-to-treat nail and scalp psoriasis: results of 2 phase III randomized, controlled trials (ESTEEM 1 and ESTEEM 2)