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Concurrently, inflammatory factors and oxidative stress pathologically activate nuclear receptor coactivator 4 (NCOA4)-mediated ferritinophagy

Interestingly, VGLUT1 and 2 are also expressed in glial cells and may play a role in the recently-identified release of glutamate from depolarized astrocytes (Bezzi et al., 2004

doi:10.2337/dc17-0280 Boscari F, Vettoretti M, Cavallin F, et al

Programmed cell death (PCD) manifests in various guises, each with its own distinctive features shaped by unique molecular pathways, and these forms often cross paths in complex ways (136)