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What made it even more effective is that it did not affect the activity of any other enzymes in the metabolic cycles which reduced the risks of any potential side-effects

They aid in promoting the synthesis of collagen and elastin and support skin repair

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The doses used in trials were around 500ug/kg, which means a 100kg person was receiving 50mg of the peptide daily. $50 million in research and development down the drain for a promising product that was no longer a viable pharmaceutical product

Other metabolic side effects could be hypokalemia (low potassium levels in the body), extreme thirst, rapid weight gain, frequent urination and/or unexplained bleeding or bruising

But polyamine biosynthesis is a pathway that eats SAM