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Clinical Trial based on IL-1receptor antagonist therapy A phase 2/3, Randomized, open-label, parallel group, 3-arm, multicenter study is going on in Sweden (NCT04324021) to understand the efficacy and safety of emapalumab and anakinra in reducing hyperinflammation and respiratory distress in patients with COVID-19 infection 61

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Once thawed: Centrifuge briefly (30 seconds at 10,000 rpm) to collect any condensation from the tube walls Prepare fresh dilutions in the desired experimental buffer (PBS, cell culture media, etc.) Maintain on ice during experiment setup Use within 24 hours of dilution