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Kinetic stability of cystathionine beta-synthase can be modulated by structural analogs of S-adenosylmethionine: potential approach to pharmacological chaperone therapy for homocystinuria

When paired with complementary bioactives, these effects broaden PCOS-linked failures, namely OS, insulin resistance, and hyperandrogenism

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Clinicians can frame these outcomes as supportive and adjunctive rather than curative, emphasizing that GHK-Cu enhances the results of a comprehensive regimen rather than replacing cornerstone interventions such as sun protection, neuromodulators, or energy-based devices