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doi: 10.1038/s41467-019-13668-3 17

Strategies to prevent the type 2 diabetes mellitus epidemic

To further verify that MOR-expressing neurons in PVN mediate morphine-induced constipation, we constructed a Cre-dependent AAV virus expressing Oprm1 short-hairpin RNAs (shMOR) to induce MOR knockdown specifically in PVN Glu neurons

In mitochondria, molecular oxygen is consumed to synthesize adenosine triphosphate via a series of coupled proton and electron transfer reactions in the physiological process