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keywords Introduction Copper is an essential redox-active micronutrient that serves as a critical cofactor for a vast array of enzymes governing fundamental biological processes, including mitochondrial respiration, antioxidant defense, and signaling cascades 1

Hasan et al., 2019)

The second way of course is reducing exposure

420,421 Another limitation of CPPs is their limited clinical efficacy, often requiring high concentrations and doses to achieve a therapeutic effect, which can cause significant toxicity and side effects, hindering the development of clinical applications

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Meanwhile, a decreased total antioxidant capacity, reduced vitamin A and E levels, and a diminished activity of the main antioxidant enzymes were also detected in these patients (4)