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[Crossref] [PubMed] Stewart CA, Yafi FA, Knoedler M, et al

In 2005, Abraham et al

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Unlike other weight loss medications that target only one incretin hormone, Tirzepatides dual action on both GLP-1 and GIP receptors offers a more robust mechanism for reducing body weight and improving metabolic health

This mechanism both inhibits cardiomyocyte apoptosis and promotes angiogenesis, thereby significantly improving cardiac function in infarcted rat models