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Gwnymi odbiorcami tego zwizku s nerki, mzg, puca, serce, jelita, minie i komrki krwi (erytrocyty i leukocyty)

Moreover, studies have found that compared to healthy controls, PCOS patients exhibit downregulated expression of genes including ferritin heavy chain 1 (FTH1), HAMP, GPX4, A2M, and HP, and upregulated expression of nuclear receptor coactivator 4 (NCOA4), along with enhancement in lipid peroxidation, serum ferritin, and total protein content, and inhibition in peroxidase activity (140)

These enzymes are encoded by the superfamily of CYP genes

Analogously, KRAS inhibitors (Sotorasib) targeting the G12C mutation and eprenetapopt (APR-246), a novel drug for Tp53 -mutant MDS and AML, both are representatives of this molecules

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