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Mechanism of Action: Receptor Binding:Ipamorelin's non-proteinogenic residues (particularly the bulky D-2-naphthylalanine) fit precisely into the hydrophobic binding pocket of GHS-R1a, creating a high-affinity, selective interaction

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This becomes concerning when considering the staggering prevalence of higher-than-normal blood pressure: up to half of adults worldwide have blood pressure levels ranging from 120/80 to 139/89 mm Hg