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In hTYR, the hydroxylphenyl group of Arbutin_c, which originally coordinated with CuA, shifts and instead coordinates with CuB during the simulation (Fig

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2a, d, c, f), while the epithelial cell neutralizing titers were lower in the mice in the 10 g/1 g and 10 g/0.1 g at week 8 (Fig

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