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Transcription factor NKX21 fuels cancer cell proliferation and survival by hyperactivating serine/glycine synthesis, highlighting this pathway as a novel therapeutic target in NKX21-positive cancers

Studies have documented its effects on the hypothalamic-pituitary-adrenal (HPA) axis and its ability to stabilise enkephalins in blood serum, contributing to its anxiolytic mechanism of action

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ATP13A2 is a P type ATPase generally found in the membranes of acidic vesicles in neurons which, along with the other two more common class of Zinc transporters belonging to the ZnT (SLC30) and ZIP (SLC39) families, is entrusted to serve exactly this role (van Veen et al., 2014)

CBX4 plays a bidirectional role in transcriptional regulation and lung adenocarcinoma progression