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When vitamin C donates electrons to neutralize free radicals, glutathione can restore vitamin C to its active form, and vitamin C can do the same for glutathione, creating a continuous antioxidant cycle

Supplementation may be necessary

This capacity usually originates from the replacement of the catalytic serine or tyrosine residues in the active site motif by a cysteinyl residue as demonstrated for mammalian, insect and fungal Omega GSTs (GSTOs) (Board et al., 2006

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H., Maletic, V

A change in one is not a change in the others