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Zoccolella S, et al

Other potential strategies to address therapeutic resistance are summarized in (59)

1, 2 Ferroptosis can be triggered by inhibition of the plasma membrane cystine/glutamate antiporter system x c - or the glutathione-dependent lipid hydroperoxidase glutathione peroxidase 4 (GPX4)

Vin Uong Bo Sung Daitea L-Glutathione c gi trong cc l h nh, nn rt thun tin mang vo trong ti ng thuc hoc ti o khoc

Upon exposure to DNA damage-inducing stimuli such as ionizing radiation, the RAD51 Cys319 site undergoes oxidation, allowing it to polymerize with PRDX1, thereby facilitating the formation of RAD51 foci