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The serum supernatant is then filtered and assessed for a variety of quality controls including residual microbial or viral contamination, endotoxin, immunoglobulin content, and total protein, before being bottled and sold commercially, at prices exceeding $1000 USD per liter (at time of writing, July 2019) depending on quality control parameters (some described later), which vary by industry and use-case

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Unexpectedly, none of the patients were affected by premature breakdown of red blood cells, known as haemolytic anaemia, which is a key clinical feature of patients with GSS mutations