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Hanaford A, Johnson SC (2022) The immune system as a driver of mitochondrial disease pathogenesis: a review of evidence

Elevated ferrous ions and iron homeostasis imbalances can further increase ROS through the Fenton reaction, also contributing to ferroptosis

doi: 10.1002/ardp.202300569 46 NygaardGFiresteinGS

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maximal respiration induced by the substrate + ADP), and state 4 corresponds to the consumption rate upon oligomycin A addition (i.e

Doses are adjusted by healthcare providers depending on medical condition, body weight, and treatment objectives