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The presence of benzyl alcohol helps inhibit the growth of microorganisms once the vial is accessed

Jung et al., 2021)

Subsequently, bone marrow suppression occurs and leukocyte count will fall around day 3 to 5 with a nadir seen around day 9

For example, the expression of GOT1 was suppressed by hypoxia-inducible factor-1 (HIF-1) in VHL-deficient human renal carcinoma (43), and by electron transport chain (ETC) in human Raji lymphoma and KMS-26 multiple myeloma (38, 53), leading to impaired proliferation of cancer cells