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Furthermore, we investigated the association of IGF-1 serum concentration with prognosis of ALS in a cohort-design in ALS-cases only

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Fluorescence was measured at 4, 24, 48 and 72 h after treatment at 485 nm excitation and 530 nm emission on a SpectraMax M3 microplate reader (Molecular Devices)

[] This PDK-mediated inhibition of pyruvate dehydrogenase shifts mitochondrial metabolism toward reduced glucose oxidation and increased uncoupled glycolysis, promoting RV fibroblasts (RVfib) proliferation, collagen production, and ultimately right ventricular fibrosis and failure

Low blood levels of the vitamin have been linked to several health problems

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