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It can also be associated with gliosis in the affected area or alter the integrity of the blood-brain barrier resulting in inflammatory events and altered tissue vascularization (Stephenson et al., 2014)

The lessons learned from astrocyte-targeted strategies provide a natural transition to examining microglia, whose dual role as immune defenders and potential drivers of pathology makes them equally compelling therapeutic targets (Figure 5)

The accumulation of cytoplasmic TDP-43 aggregates is considered a late-stage event in neurodegeneration

Research indicates that the body's regulation of glutathione levels ensures that its presence in breast milk supports the antioxidant needs of the baby

1-propanaminium, 3-carboxy-2-hydroxy-n,n,n-trimethyl-, Inner Salt, (2r)- 55