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How does ischemia-reperfusion injury coordinate its effects across different organs, and through what pathways

RELN encodes Reelin, a glycoprotein that plays an important role in synaptic function and is a ligand for lipoprotein receptors such as very low-density lipoprotein receptor (VLDLR) and apolipoprotein E receptor 2 (ApoER2

doi: 10.1210/en.2010-1468 [DOI] [PubMed] [Google Scholar] 442

Biochemistry of Lipids, Lipoproteins and Membranes

This method requires a polynucleotide which codes for a polypeptide of the invention that operatively linked to a promoter and any other genetic elements necessary for the expression of the polypeptide by the target tissue

In 1982, Holst and, separately, Dominique Bataille, a French endocrinologist based at INSERM in Montellier, France, together with Mutt isolated a smaller peptide from L-cells