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Selective oestrogen receptor modulation: molecular pharmacology for the millennium

The BCAAs are necessary for the growth and survival of Mtb [223, 224], and enzymes participating in the biosynthetic pathway of BCAAs have been proposed as potential drug targets [222]

We discovered a glutathione regulator in the ER that likely plays a key role in these conditions. That regulator, they learned, acts as a crucial proofreader, ensuring proteins in the ER are folded correctly