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5 Disruption of the neuroendocrine network and the local biochemical microenvironment The pathological microenvironment of Chronic Prostatitis/Chronic Pelvic Pain Syndrome (CP/CPPS) involves not only inflammatory-immune crosstalk and oxidative stress, but alterations in local biochemical components and dysregulation of the neuroendocrine network also represent crucial links in the impairment of sperm development

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If no population health measure has a benchmark or meets the case minimum requirement, each such measure is excluded from the MVP participant's total measure achievement points and total available measure achievement points

Journal of controlled release : official journal of the Controlled Release Society

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