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The reduction of TH activity could be secondary to the degeneration of dopaminergic neurons in PD

Research indicates that SCD activity may play a key role in melanoma phenotype switching: under low SCD conditions, ER stress is induced, suppresses microphthalmia-associated transcription factor (MITF), and promotes melanoma dedifferentiation (Vivas-Garca et al., 2020)

Activation of lung p53 by Nutlin-3a prevents and reverses experimental pulmonary hypertension

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has demonstrated that hypertensive patients have a higher International Prostate Symptom Score (IPSS) and larger prostate volume than normotensive men, indicating the association between hypertension and male LUTS (103)

Int J Ophthalmol 10:13081318