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The mice brains were then fixed in 4% paraformaldehyde for 24 h and embedded in paraffin

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GlyProAla sits clearly in the second category: biologically plausible, increasingly supported, but not yet definitive

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1) may reflect, at least in some instances, potential target engagement by omaveloxolone leading to the transient increases in aminotransferases observed in MOXIe Part 2 [16, 20, 22,23,24]