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As we proposed at 427.501(d) and noted in the CY 2025 PFS proposed rule (89 FR 61956), we believe it is necessary and appropriate for CMS to recalculate the rebate amount for an applicable calendar quarter at a regular interval to include updated information about key data elements included in the calculation of the rebate amount

In general, these men are active in life and would like to remain sexually active

This is particularly important for patients who take multiple high-cost drugs

This improves the quality of life for patients

Cosmetic applications often benefit from injectable therapy's faster onset and targeted delivery

[DOI] [PubMed] [Google Scholar] 75.Szabo S., Vattay P., Scarbrough E., Folkman J