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Taken together, our work suggests that the glutamine-glutamate cycle and KRAS-dependent modulation of FOXO signalling are potentially attractive new targets for validation studies in more clinically relevant models and drug discovery

This leads to the production of free radicals, destroying mitochondria, affecting energy metabolism, and forming a vicious cycle

10.1152/physrev.00023.2017 Physiol Rev

Deductions about the number, organization, and evolution of genes in the tomato genome based on analysis of a large expressed sequence tag collection and selective genomic sequencing

doi: 10.3390/ijerph21091242., 51

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