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The expression and activation of YAP and YY1 in the endothelium is triggered by shear stress alterations, and both TFs exert pro-atherogenic effects in vivo, which [43, 44] could be further enhanced by lactylation

However, a critical question arises: is Complex I deficiency a universal primary event in PD, or a secondary phenomenon under specific etiologies (e.g., environmental toxin exposure, certain gene mutations)

Glutathione acts as a potent antioxidant that helps neutralise harmful free radicals and protect cells from oxidative damage

Porporato P

The crystal structures of human catalase show that the active site iron is pentacoordinated

Sex differences in mortality from COVID-19 pandemic: are men vulnerable and women protected