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68,69 Indeed, the pathogenesis of many diseases without clear protein targets is related to non-coding RNA, which can be used to predict the advantages of ASO in treating diseases

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10.1016/j.toxlet.2005.05.008 110 PacherP.BeckmanJ

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Pancreatic cancer is one of the most difficult cancers to treat largely because of the inability of anticancer drugs to penetrate the malignant tissue as a result of the dense ECM (167)

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