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Hu J, Locasale JW, Bielas JH, OSullivan J, Sheahan K, Cantley LC, et al

doi: 10.1101/2024.09.19.613992 60

Maintain Proper Oral Hygiene - Brush the teeth twice a day for two minutes at a time and clean the tongue

Neuron 72 : 7285

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The pathogenetic mechanisms underlying this syndrome include disruption of hunger/satiety centers (damage to arcuate, ventromedial, and paraventricular hypothalamic nuclei), leptin resistance despite elevated circulating leptin levels, autonomic dysregulation with reduced energy expenditure, hypothalamic-pituitary axis dysfunction, and local inflammatory processes [87, 88]