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Oct 2 2023;14(19):8951-8963

J Cell Physiol 182:163170 Srinivasan R, Ratiney H, Hammond-Rosenbluth KE, Pelletier D, Nelson S (2010) MR spectroscopic imaging of glutathione in the white and gray matter at 7 T with an application to multiple sclerosis

Factors responsible for the liver's contribution to drug metabolism include that it is a large organ, that it is the first organ perfused by chemicals absorbed in the gut, and that there are very high concentrations of most drug-metabolizing enzyme systems relative to other organs