It is the outcome of thyroid hormones impact on all aspects of lipid metabolism, resulting in quantitative and/or qualitative alterations in triglycerides, cholesterol, and other lipoproteins 71
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It enhances both cell and humoral mediated immunity and is involved in the regulation of homocysteine

Disclosure of interest: Kanjana Perera: nothing to disclose E-Posters - DIAGNOSIS / ETIOLOGY 04.00 - DIAGNOSIS / ETIOLOGY - 04.01 - DIAGNOSIS/INVESTIGATION OF STROKE ETIOLOGY P2452 - ESOC25-2483 THE ROLE OF D-DIMER AND FIBRINOGEN BLOOD LEVELS IN IDENTIFYING STROKE ETIOLOGY: INSIGHTS FROM AN OBSERVATIONAL STUDY Miriam Caterino 1 , Annachiara Zara 1 , Mariarosaria Alberico 1 , Pantaleone Sirignano 1 , Paolo Barone 1 , Rosa Napoletano 1 1 AOU Ruggi d'Aragona, Salerno, Italy Background and Aims: Stroke is one of the leading causes of death and disability.Etiological diagnosis is essential for optimal patient management.Serum biomarkers such as D-Dimer and Fibrinogen are known for their roles in coagulation and inflammatory response,but their potential in determining stroke etiology remains underexplored.The aim of this study is to assess whether D-Dimer and Fibrinogen levels can be used to identify stroke etiology,contributing to a rapid and accurate diagnosis

After the reaction with H 2 O 2 , the oxidized Prx is reduced back by the reaction with Trx, while the oxidized GPx is reduced back mainly by the reaction with GSH [38]
In vitro testing confirmed that MSU crystals trigger the manifestation of macrophage rs45520937 and amplify the expression of NLRP3 and IL-1 (44)